Search on: ALKB HOMOLOG 1, HISTONE H2A DIOXYGENASE 
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Descriptor English:   AlkB Homolog 1, Histone H2a Dioxygenase 
Descriptor Spanish:   Histona H2a Dioxigenasa, Homólogo 1 de Alkb 
Descriptor Portuguese:   Homólogo AlkB 1 da Histona H2a Dioxigenase 
Synonyms English:   ALKBH Protein
Alkylated DNA Repair Protein AlkB Homolog 1
Alpha-Ketoglutarate-Dependent Dioxygenase ABH1
DNA Lyase ABH1
DNA Oxidative Demethylase ALKBH1
ABH1, Alpha-Ketoglutarate-Dependent Dioxygenase
ABH1, DNA Lyase
Alpha Ketoglutarate Dependent Dioxygenase ABH1  
Tree Number:   D08.811.074.062.500
D08.811.682.690.416.139.500
Definition English:   A dioxygenase and alkylation repair homolog that functions by oxidative demethylation in RNA and DNA REPAIR of substrates which contain 3-methylcytosine. It also functions as one of the HISTONE DEMETHYLASES involved in embryonic development and maintaining the pluripotency of EMBRYONIC STEM CELLS. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56459 
Unique Identifier:   D000071498 

Occurrence in VHL:
 

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